The emerging role of systems biology for engineering protein production in CHO cells

Volume: 51, Pages: 64 - 69
Published: Jun 1, 2018
Abstract
To meet the ever-growing demand for effective, safe, and affordable protein therapeutics, decades of intense efforts have aimed to maximize the quantity and quality of recombinant proteins produced in CHO cells. Bioprocessing innovations and cell engineering efforts have improved product titer; however, uncharacterized cellular processes and gene regulatory mechanisms still hinder cell growth, specific productivity, and protein quality. Herein,...
Paper Details
Title
The emerging role of systems biology for engineering protein production in CHO cells
Published Date
Jun 1, 2018
Volume
51
Pages
64 - 69
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