Antitussive and expectorant activities of licorice and its major compounds
Abstract
Licorice has been used as an antitussive and expectorant herbal medicine for a long history. This work evaluated the activities of 14 major compounds and crude extracts of licorice, using the classical ammonia-induced cough model and phenol red secretion model in mice. Liquiritin apioside (1), liquiritin (2), and liquiritigenin (3) at 50 mg/kg (i.g.) could significantly decrease cough frequency by 30-78% (p < .01). The antitussive effects could...
Paper Details
Title
Antitussive and expectorant activities of licorice and its major compounds
Published Date
Jan 1, 2018
Volume
26
Issue
1
Pages
278 - 284
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Notes
History