Unmasking Amides: Ruthenium-Catalyzed Protodecarbonylation of N-Substituted Phthalimide Derivatives

Volume: 19, Issue: 23, Pages: 6404 - 6407
Published: Nov 20, 2017
Abstract
The unprecedented transformation of a wide range of synthetically appealing phthalimides into amides in a single-step operation has been achieved in high yields and short reaction times using a ruthenium catalyst. Mechanistic studies revealed a unique, homogeneous pathway involving five-membered ring opening and CO2 release with water being the source of...
Paper Details
Title
Unmasking Amides: Ruthenium-Catalyzed Protodecarbonylation of N-Substituted Phthalimide Derivatives
Published Date
Nov 20, 2017
Volume
19
Issue
23
Pages
6404 - 6407
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