Augmentation of Labor: A Review of Oxytocin Augmentation and Active Management of Labor

Published on Dec 1, 2017in Obstetrics and Gynecology Clinics of North America2.844
· DOI :10.1016/J.OGC.2017.08.012
Annessa Kernberg3
Estimated H-index: 3
(OHSU: Oregon Health & Science University),
Aaron B. Caughey95
Estimated H-index: 95
(OHSU: Oregon Health & Science University)
Sources
Abstract
: Labor augmentation can be used to hasten labor, shorten the time to delivery, and perhaps reduce the risk of cesarean delivery. Particularly in women with longer labors or less frequent contractions, oxytocin augmentation seems to have positive impacts on these outcomes. Despite this, the evidence for augmentation alone on the risk of cesarean delivery is unclear, with varying evidence. More recently, oxytocin protocols have been recommended to standardize care and ensure patient safety.
📖 Papers frequently viewed together
19932.89Human Nature
1 Author (Peter Curtis)
References20
Newest
AbstractObjective: To examine the outcomes of vaginal birth after cesarean (VBAC) in women, in spontaneous labor, delivering after 37 weeks’ gestation at an institution where trial of labor after a previous cesarean delivery (TOLAC) is encouraged and management of labor is standardized.Methods: This retrospective cohort study included 3071 women with one previous cesarean only and no vaginal delivery who underwent a trial of labor from 2001 to 2011. Women were managed using the standardized “act...
Source
Midwifery Unit Managers completed surveys in 2008 and 2014 to determine methods of induction of labour. There was an increase in balloon catheter use for cervical ripening (rate difference 37%, P = 0.007). Currently, all respondent hospitals have an oxytocin protocol; district hospitals had a significant increase in use of post-maturity protocols (rate difference = 40%, P = 0.01) but there was no change in use of prostaglandin protocols.
Source
#1C. Loscul (Paris V: Paris Descartes University)H-Index: 2
#2A A Chantry (Paris V: Paris Descartes University)H-Index: 9
Last. C. Le Ray (Paris V: Paris Descartes University)H-Index: 11
view all 6 authors...
ResumeObjectif Evaluer l’association entre la duree des intervalles d’augmentation de l’oxytocine au cours du travail spontane et le risque d’hemorragies du post-partum (HPP). Materiel et methodes Etude de cohorte retrospective, de primipares en travail spontane ayant recu de l’oxytocine pendant le travail (n = 454). Les modalites d’administration de l’oxytocine ont ete analysees, en particulier la duree des intervalles entre deux augmentations du debit d’oxytocine (< 20 minutes ou ≄ 20 minutes)...
Source
#1Janne Rossen (NTNU: Norwegian University of Science and Technology)H-Index: 5
#2T. B. Østborg (Stavanger University Hospital)H-Index: 7
Last. TorbjĂžrn Moe EggebĂž (Stavanger University Hospital)H-Index: 24
view all 5 authors...
A protocol including judicious use of oxytocin augmentation was investigated to determine whether it would change how oxytocin was used and eventually influence labor and fetal outcomes.The population of this cohort study comprised 20 227 delivering women with singleton pregnancies ≄37 weeks, cephalic presentation, spontaneous or induced onset of labor, without previous cesarean section. Women delivering from 2009 to 2013 at Stavanger University Hospital, Norway, were included. Data were collect...
Source
#1P. BorH-Index: 1
#2S. LedertougH-Index: 1
Last. I. StornesH-Index: 1
view all 5 authors...
Objective To investigate whether discontinuation of oxytocin infusion increases the duration of the active phase of labour and reduces maternal and neonatal complications. Design Randomised controlled trial. Setting Department of Obstetrics and Gynaecology, Regional Hospital of Randers, Denmark. Population Women with singleton pregnancy in the vertex position undergoing labour induction or augmentation. Methods Two hundred women were randomised when cervical dilation was ≀4 cm to either continue...
Source
#1Brady E HamiltonH-Index: 50
#2Joyce A MartinH-Index: 67
Last. T J MatthewsH-Index: 9
view all 5 authors...
This report presents 2014 data on U.S. births according to a wide variety of characteristics. Data are presented for maternal age, live-birth order, race and Hispanic origin, marital status, attendant at birth, method of delivery, period of gestation, birthweight, and plurality. Birth and fertility rates are presented by age, live-birth order, race and Hispanic origin, and marital status. Selected data by mother's state of residence and birth rates by age and race of father also are shown. Trend...
Abstract Objective To review the most current literature in order to provide evidence-based recommendations to obstetrical care providers on induction of labour. Options Intervention in a pregnancy with induction of labour. Outcomes Appropriate timing and method of induction, appropriate mode of delivery, and optimal maternal and perinatal outcomes. Evidence Published literature was retrieved through searches of PubMed, CINAHL, and The Cochrane Library in 2010 using appropriate controlled vocabu...
Source
#1Sara Kenyon (University of Birmingham)H-Index: 29
#2Hironobu TokumasuH-Index: 2
Last. Rintaro MoriH-Index: 63
view all 5 authors...
Background A major cause of failure to achieve spontaneous vaginal birth is delay in labour due to presumed inefficient uterine action. Oxytocin is given to increase contractions and high-dose regimens may potentially increase the number of spontaneous vaginal births, but as oxytocin can cause hyperstimulation of the uterus, there is a possibility of increased adverse events. Objectives To compare starting dose and increment dose of oxytocin for augmentation for women delayed in labour to determ...
Source
#1Edward Hayes (Thomas Jefferson University)H-Index: 8
#2Louis Weinstein (Thomas Jefferson University)H-Index: 6
Oxytocin is 1 of the most commonly used drugs in labor and has been associated with adverse maternal and fetal outcomes. In an attempt to improve patient safety, we constructed a standardized protocol for labor induction with oxytocin. We reviewed the numerous publications regarding oxytocin use for either induction or augmentation of labor in order to determine if there was a protocol available that would maximize success of delivery and minimize the adverse maternal and fetal effects of the dr...
Source
#1M.C. Svanström (UmeÄ University)H-Index: 1
#2Björn Biber (UmeÄ University)H-Index: 26
Last. E.M. BĂ„lfors (KI: Karolinska Institutet)H-Index: 1
view all 6 authors...
BACKGROUND: ECG changes, similar to those seen during myocardial ischaemia, together with symptoms of chest pain, are common during Caesarean section (CS). We hypothesized that oxytocin administrat ...
Source
Cited By15
Newest
#1Uri Amikam (Tel Aviv Sourasky Medical Center)H-Index: 6
#2Liran Hiersch (Tel Aviv Sourasky Medical Center)H-Index: 20
Last. Nir Melamed (Sunnybrook Health Sciences Centre)H-Index: 34
view all 4 authors...
Medically-indicated deliveries are common in twin pregnancies given the increased risk of various obstetric complications in twin compared to singleton pregnancies, mainly hypertensive disorders of pregnancy and foetal growth restriction. Due to the unique characteristics of twin pregnancies, the success rates and safety of labour induction may be different than in singleton pregnancies. However, while there are abundant data regarding induction of labour in singleton pregnancies, the efficacy a...
Source
#1D. T. Monks (WashU: Washington University in St. Louis)H-Index: 4
#2Arvind Palanisamy (WashU: Washington University in St. Louis)H-Index: 12
Oxytocin is one of the most commonly used medications during labour and delivery. Recent insights from basic neuroscience research suggest that the uterotonic effects of oxytocin may arguably be trivial when compared with its profound effects on higher-order human behaviour. The purpose of this review is to highlight the potential consequences of manipulating oxytocinergic signalling during the peripartum period and its long-term impact on the maternal-infant dyad. We identified four domains whe...
Source
#1Megan Marx Delaney (Harvard University)H-Index: 6
#2Tapan Kalita (Population Services International)H-Index: 4
Last. Katherine Semrau (Harvard University)H-Index: 28
view all 10 authors...
OBJECTIVE To understand the prevalence of intrapartum oxytocin use, assess associated perinatal and maternal outcomes, and evaluate the impact of a WHO Safe Childbirth Checklist intervention on oxytocin use at primary-level facilities in Uttar Pradesh, India. DESIGN Secondary analysis of a cluster-randomised controlled trial. SETTING Thirty Primary and Community public health facilities in Uttar Pradesh, India from 2014 to 2017. POPULATION Women admitted to a study facility for childbirth at bas...
Source
#1Lisa D. Levine (UPenn: University of Pennsylvania)H-Index: 15
#2Katheryne DownesH-Index: 27
Last. Sindhu K. Srinivas (UPenn: University of Pennsylvania)H-Index: 25
view all 4 authors...
AbstractObjective: Our objective was to evaluate the impact of a standardized induction protocol on reducing maternal and neonatal morbidity in women undergoing an induction with an unfavorable cer...
Source
#1Antonio Schiattarella (Seconda UniversitĂ  degli Studi di Napoli)H-Index: 11
#2Gaetano Riemma (Seconda UniversitĂ  degli Studi di Napoli)H-Index: 9
Last. Maddalena Morlando (Seconda UniversitĂ  degli Studi di Napoli)H-Index: 14
view all 7 authors...
BACKGROUND Protracted labor is associated with an elevated risk of maternal and fetal complications. Results of randomized controlled trials on the efficacy in labor of phloroglucinol (PHL), a pure antispasmodic drug, are uncertain. OBJECTIVES To evaluate whether PHL is effective in shortening the first stage of labor. SEARCH STRATEGY MEDLINE, EMBASE, LILACS, Scopus, ClinicalTrials.gov, and the Cochrane Library were searched from inception to July 2020. SELECTION CRITERIA Randomized controlled t...
Source
#1Aude Girault (University of Paris)H-Index: 2
#2BĂ©atrice Blondel (University of Paris)H-Index: 53
Last. Camille Le Ray (University of Paris)H-Index: 23
view all 4 authors...
BACKGROUND The objective of this study was to describe labor duration of women managed with current obstetric practices in a French national population-based cohort and to assess the association of age and BMI on this duration. METHODS All women in the French perinatal survey of 2016 with a singleton cephalic fetus, delivering at term after a spontaneous labor were included. Duration of labor was defined as time between admission to the labor ward and birth. Duration of total labor and first and...
Source
#1Aude Girault (University of Paris)H-Index: 2
#2BĂ©atrice Blondel (University of Paris)H-Index: 53
Last. Camille Le Ray (University of Paris)H-Index: 23
view all 4 authors...
Introduction While use of augmentation of labor (AL) is appropriate for labor dystocia, it is frequently used inadequately and unnecessarily. The objective was to assess at a national level, the frequency and determinants of misuse of augmentation of labor (AL). Material and methods Women of the French perinatal survey of 2016 with a singleton cephalic fetus, delivering at term after a spontaneous labor were included. “Misuse of AL” was defined by artificial rupture of the membranes (ROM) and/or...
Source
#1Rehab Abdelhamid Aboshama (FU: Fayoum University)H-Index: 1
#2Ahmed Mohamed Abdelhakim (Cairo University)H-Index: 5
Last. Mohamed Sobhy Bakry (FU: Fayoum University)H-Index: 2
view all 9 authors...
OBJECTIVES To compare the safety and efficacy between high dose and low dose oxytocin administration for labor augmentation. METHODS We searched for the available studies during March 2020 in PubMed, Cochrane Library, Scopus, and ISI Web of science. All randomized clinical trials (RCTs) that assessed safety and efficacy of high dose vs. low dose oxytocin for labor augmentation were considered. The extracted data were entered into RevMan software. Dichotomous and continuous data were pooled as od...
Source
#1Vasilios Pergialiotis (UoA: National and Kapodistrian University of Athens)H-Index: 22
#2Ioannis Bellos (UoA: National and Kapodistrian University of Athens)H-Index: 13
Last. George Daskalakis (UoA: National and Kapodistrian University of Athens)H-Index: 20
view all 6 authors...
BACKGROUND Oxytocin infusion prior to confirmation of delay in labor is discouraged by the World Health Organization. However, evidence from the Cochrane library seems to support early amniotomy and oxytocin to reduce the rates of cesarean sections (CS). OBJECTIVES To investigate differences in mode of delivery among parturient receiving early versus delayed oxytocin infusion following amniotomy as a mean for augmentation of labor. SEARCH STRATEGY We searched Medline, Scopus, EMBASE, Cochrane Ce...
Source
#1Rebecca R S Clark (Leonard Davis Institute of Health Economics)H-Index: 1
#2Nicole Warren (Johns Hopkins University)H-Index: 10
Last. Phyllis Sharps (Johns Hopkins University)H-Index: 35
view all 6 authors...
Introduction To examine whether there is a threshold of oxytocin exposure at which the risk for primary cesarean increases among women who are nulliparous with a term, singleton, vertex fetus (NTSV) and how oxytocin interacts with other risk factors to contribute to this outcome. Methods This was a secondary analysis of the Consortium on Safe Labor data set that used a retrospective cohort study design. Women who met the criteria for NTSV who were not admitted for a prelabor cesarean and for who...
Source
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.