[P4-273]: TAU BURDEN IN OREXINERGIC WAKE-PROMOTING NEURONS IN ALZHEIMER'S DISEASE IN COMPARISON TO CORTICAL BASAL DEGENERATION AND PROGRESSIVE SUPRANUCLEAR PALSY: A NEUROPATHOLOGICAL IMPLICATION IN SLEEP DISTURBANCES
Volume: 13, Issue: 7S_Part_28
Published: Jul 1, 2017
Abstract
The neurobiological basis of sleep disturbances in tauopathies is currently unknown. Degeneration and/or malfunction of wake-and-sleep promoting neurons have been suspected to aggravate sleep dysfunction. AD patients experience fragmented sleep and daytime-somnolence. Progressive supranuclear palsy (PSP) patients show generalized sleep reductions (REM and non-REM); corticobasal degeneration (CBD) patients show variable profiles. Orexinergic...
Paper Details
Title
[P4-273]: TAU BURDEN IN OREXINERGIC WAKE-PROMOTING NEURONS IN ALZHEIMER'S DISEASE IN COMPARISON TO CORTICAL BASAL DEGENERATION AND PROGRESSIVE SUPRANUCLEAR PALSY: A NEUROPATHOLOGICAL IMPLICATION IN SLEEP DISTURBANCES
Published Date
Jul 1, 2017
Volume
13
Issue
7S_Part_28
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