Transcatheter and Surgical Management of Mitral Paravalvular Leak: Long-Term Outcomes

Published on Oct 9, 2017in Jacc-cardiovascular Interventions8.432
· DOI :10.1016/J.JCIN.2017.07.046
Mohamad Alkhouli24
Estimated H-index: 24
(WVU: West Virginia University),
Charanjit S. Rihal96
Estimated H-index: 96
(Mayo Clinic)
+ 10 AuthorsSameh M. Said24
Estimated H-index: 24
(Mayo Clinic)
Abstract Objectives The aim of this study was to report the use trends and immediate and long-term outcomes of a large cohort of patients who underwent redo surgery or transcatheter repair of paravalvular leaks (PVLs) at a tertiary referral center. Background Percutaneous treatment of mitral PVL has emerged as an alternative to surgical treatment in high-risk surgical candidates. There are limited data on the utilization trends, safety, and efficacy of both procedures in the management of mitral PVL. Methods Patients who underwent treatment of mitral PVL at the Mayo Clinic between January 1995 and December 2015 were enrolled. Utilization trends, procedural details, technical success, and in-hospital and long-term outcomes were assessed. Results Three hundred eighty-one patients underwent percutaneous (n = 195) or surgical (n = 186) treatment of mitral PVLs. The mean age was 66 ± 12 years, and 37% of patients had bioprosthetic valves. Technical success was higher in the surgical group (95.5% vs. 70.1%; p  Conclusions In contemporary practice, patients with symptomatic mitral PVLs are best treated with an integrated team approach incorporating both surgical and percutaneous techniques. Patient selection and timing of intervention are critical to achieve optimal results.
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