Original paper
In vivo MRI assessment of the human locus coeruleus along its rostrocaudal extent in young and older adults
Abstract
The locus coeruleus (LC), a major origin of noradrenergic projections in the central nervous system (CNS), may serve a critical role in the pathogenesis of neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD). As such, there is considerable interest to develop magnetic resonance imaging (MRI) techniques to assess the integrity of the LC in vivo. The high neuromelanin content of the LC serves as an endogenous...
Paper Details
Title
In vivo MRI assessment of the human locus coeruleus along its rostrocaudal extent in young and older adults
Published Date
Dec 1, 2017
Journal
Volume
163
Pages
150 - 159
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Notes
History