TE dependent Diffusion Imaging (TEdDI) distinguishes between compartmental T2 relaxation times

Biophysical modeling of macroscopic diffusion-weighted MRI signal in terms of microscopic cellular parameters holds the promise of quantifying the integrity of white matter. Unfortunately, even fairly simple multi-compartment models of proton diffusion in the white matter do not provide a unique, biophysically plausible solution. Here we report a nontrivial diffusion MRI signal dependence on echo time (TE) in human white matter in vivo. We...