Retrosplenial cortex

Cognitive psychology

Neuroscience

Cortex (anatomy)

Episodic memory

Working memory

Cognition

Cognitive map

Spatial cognition

Computer science

Spatial memory

Cognitive science

Psychology

Spatial relation

Artificial intelligence

Landmark

Brain and Neuroscience Advances

Retrosplenial cortex is a region within the posterior neocortical system, heavily interconnected with an array of brain networks, both cortical and subcortical, that is, engaged by a myriad of cognitive tasks. Although there is no consensus as to its precise function, evidence from both human and animal studies clearly points to a role in spatial cognition. However, the spatial processing impairments that follow retrosplenial cortex damage are not straightforward to characterise, leading to difficulties in defining the exact nature of its role. In this article, we review this literature and classify the types of ideas that have been put forward into three broad, somewhat overlapping classes: (1) learning of landmark location, stability and permanence; (2) integration between spatial reference frames; and (3) consolidation and retrieval of spatial knowledge (schemas). We evaluate these models and suggest ways to test them, before briefly discussing whether the spatial function may be a subset of a more general function in episodic memory.

Retrosplenial cortex and its role in spatial cognition