Global loss of myelin water over 5 years in multiple sclerosis normal-appearing white matter
Abstract
Background: Reduced myelin water fraction (MWF, a marker for myelin), increased geometric mean T 2 (ieGMT 2 , reflecting intra/extracellular water properties), and increased T 1 (related to total water content) have been observed in cross-sectional studies of multiple sclerosis (MS) normal-appearing white matter (NAWM). Objective: To assess longitudinal changes of magnetic resonance (MR) measures in relapsing-remitting MS (RRMS) brain NAWM....
Paper Details
Title
Global loss of myelin water over 5 years in multiple sclerosis normal-appearing white matter
Published Date
Aug 7, 2017
Journal
Volume
24
Issue
12
Pages
1557 - 1568
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Notes
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