Review paper
The role of mitochondrial ROS in antibacterial immunity
Abstract
Reactive oxygen species (ROS) are essential participants of various innate immune cell responses against microorganisms and are also involved in many cellular regulatory pathways. It was believed that the main pool of ROS in the innate immune cells is generated by the NADPH oxidase enzymatic complex. However, it was discovered recently that mitochondrial ROS (mtROS) are equally important for the functioning of the immune system. mtROS play an...
Paper Details
Title
The role of mitochondrial ROS in antibacterial immunity
Published Date
Aug 3, 2017
Volume
233
Issue
5
Pages
3745 - 3754