Emerging antibody-drug conjugates for treating lymphoid malignancies
Abstract
Introduction: Antibody-drug conjugates (ADC) are monoclonal antibodies (Mabs) attached to biologically active drugs through specialized chemical linkers. They deliver and release cytotoxic agents at the tumor site, reducing the likelihood of systemic exposure and therefore toxicity. These agents should improve the potency of chemotherapy by increasing the accumulation of cytotoxic the drug within or near the neoplastic cells with reduced...
Paper Details
Title
Emerging antibody-drug conjugates for treating lymphoid malignancies
Published Date
Jul 3, 2017
Volume
22
Issue
3
Pages
259 - 273
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