Original paper
Coexistence of two main folded G-quadruplexes within a single G-rich domain in the EGFR promoter
Abstract
EGFR is an oncogene which codifies for a tyrosine kinase receptor that represents an important target for anticancer therapy. Indeed, several human cancers showed an upregulation of the activity of this protein. The promoter of this gene contains some G-rich domains, thus representing a yet unexplored point of intervention to potentially silence this gene. Here, we explore the conformational equilibria of a 30-nt long sequence located at...
Paper Details
Title
Coexistence of two main folded G-quadruplexes within a single G-rich domain in the EGFR promoter
Published Date
Jul 29, 2017
Journal
Volume
45
Issue
17
Pages
10132 - 10142
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History