A standardized extract of the fruit of Hovenia dulcis alleviated alcohol-induced hangover in healthy subjects with heterozygous ALDH2: A randomized, controlled, crossover trial

Hovenia dulcis, known as the oriental raisin tree, is mainly found in East Asia. It has long been used as traditional folk remedies for alcohol intoxication. To examine the anti-hangover effect of Hovenia dulcis Thunb. fruit extract (HDE) in a randomized controlled crossover trial. Twenty-six eligible male adults with heterozygous ALDH2 (23.7±0.3 years old) consumed 360 mL of Korean Soju (50 g alcohol) together with HDE (2460 mg) or matched...