Influence of metabolic syndrome and diabetes on progression of calcific aortic valve stenosis

Background Determinants of the progression of aortic stenosis (AS) remained unclear. Metabolic syndrome (MetS) and diabetes are suspected to play an active role but literature is scarce and results conflicting. We sought to assess their impact in an ongoing prospective cohort of asymptomatic patients with at least mild AS. Methods We enrolled 203 patients (73 ± 9 years, 75% men) with at least 2 years of follow-up. Risk-factors assessment was...