Adoptive transfer of murine T cells expressing a chimeric‐PD 1‐Dap10 receptor as an immunotherapy for lymphoma
Abstract
Adoptive transfer of T cells is a promising cancer therapy and expression of chimeric antigen receptors can enhance tumour recognition and T-cell effector functions. The programmed death protein 1 (PD1) receptor is a prospective target for a chimeric antigen receptor because PD1 ligands are expressed on many cancer types, including lymphoma. Therefore, we developed a murine chimeric PD1 receptor (chPD1) consisting of the PD1 extracellular domain...
Paper Details
Title
Adoptive transfer of murine T cells expressing a chimeric‐PD 1‐Dap10 receptor as an immunotherapy for lymphoma
Published Date
Jul 27, 2017
Journal
Volume
152
Issue
3
Pages
472 - 483
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