Encapsulation in chitosan-based polyelectrolyte complexes enhances antidiabetic activity of curcumin
Abstract
Low bioavailability, poor aqueous stability and lack of appropriate delivery systems delimit the chemotherapeutic effect of curcumin. In this study, curcumin was encapsulated in chitosan-based polyelectrolyte complexes and its antidiabetic activities were assessed using in vitro α-amylase inhibitory assay and in vivo antihyperglycaemic effect in alloxan-induced rats. Microscopic examination showed nanoformulations (<50 nm) of curcumin loaded in...
Paper Details
Title
Encapsulation in chitosan-based polyelectrolyte complexes enhances antidiabetic activity of curcumin
Published Date
Aug 1, 2017
Journal
Volume
35
Pages
584 - 594
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