Association of methadone dose with substance use and treatment retention in pregnant and postpartum women with opioid use disorder

BackgroundIn non-pregnant individuals being treated for opioid use disorder (OUD) with methadone, doses ≥60 mg per day are associated with improved treatment retention and decreased illicit opioid use. Although methadone remains the first line treatment for OUD in pregnant women, there are no studies replicating this finding in pregnancy.MethodsWe conducted a retrospective cohort study of 189 pregnant women treated with methadone for OUD from...