Reliability of White Matter Microstructural Changes in HIV Infection: Meta-Analysis and Confirmation

BACKGROUND:

Diffusion tensor imaging has been widely used to measure HIV effects on white matter microarchitecture. While many authors have reported reduced fractional anisotropy and increased mean diffusivity in HIV, quantitative inconsistencies across studies are numerous.

PURPOSE:

Our aim was to evaluate the consistency across studies of HIV effects on DTI measures and then examine the DTI reliability in a longitudinal...