Catechol- O -Methyltransferase and UDP-Glucuronosyltransferases in the Metabolism of Baicalein in Different Species

Published on May 23, 2017in European Journal of Drug Metabolism and Pharmacokinetics1.913
· DOI :10.1007/S13318-017-0419-9
Ruiya Zhang1
Estimated H-index: 1
(Dalian Medical University),
Yonglei Cui7
Estimated H-index: 7
(Dalian Medical University)
+ 9 AuthorsZhonghui Yu1
Estimated H-index: 1
(Dalian Medical University)
Sources
Abstract
Background Baicalein is the major bioactive flavonoid in some herb medicines and dietary plants; however, the detailed metabolism pathway of its major metabolite oroxylin A-7-O-β-d-glucuronide in human was not clear. It was important to illustrate the major metabolic enzymes that participate in its elimination for the clinic use of baicalein.
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