Original paper
ING3 promotes prostate cancer growth by activating the androgen receptor
Abstract
The androgen receptor (AR) is a major driver of prostate cancer, and increased AR levels and co-activators of the receptor promote the development of prostate cancer. INhibitor of Growth (ING) proteins target lysine acetyltransferase or lysine deacetylase complexes to the histone H3K4Me3 mark of active transcription, to affect chromatin structure and gene expression. ING3 is a stoichiometric member of the TIP60 lysine acetyltransferase complex...
Paper Details
Title
ING3 promotes prostate cancer growth by activating the androgen receptor
Published Date
May 16, 2017
Journal
Volume
15
Issue
1
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Notes
History