Review paper
Regulation of Metabolic Activity by p53
Abstract
Metabolic reprogramming in cancer cells is controlled by the activation of multiple oncogenic signalling pathways in order to promote macromolecule biosynthesis during rapid proliferation. Cancer cells also need to adapt their metabolism to survive and multiply under the metabolically compromised conditions provided by the tumour microenvironment. The tumour suppressor p53 interacts with the metabolic network at multiple nodes, mostly to reduce...
Paper Details
Title
Regulation of Metabolic Activity by p53
Published Date
May 20, 2017
Journal
Volume
7
Issue
2
Pages
21 - 21
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Notes
History