Gene

Context (archaeology)

Ecology

Biology

Selection (genetic algorithm)

Data mining

Computer science

Computational biology

Evolutionary biology

Paleontology

Single-nucleotide polymorphism

Genetics

Phylogenetic tree

Mathematics

Genotype

Phylogenetics

Mathematical analysis

Tree (set theory)

Genomic selection

Model selection

Machine learning

Key (lock)

Nature Methods

Model-based molecular phylogenetics plays an important role in comparisons of genomic data, and model selection is a key step in all such analyses. We present ModelFinder, a fast model-selection method that greatly improves the accuracy of phylogenetic estimates by incorporating a model of rate heterogeneity across sites not previously considered in this context and by allowing concurrent searches of model space and tree space.

ModelFinder: fast model selection for accurate phylogenetic estimates