Dynamics of DNA Knots during Chain Relaxation

Volume: 50, Issue: 10, Pages: 4074 - 4082
Published: May 8, 2017
Abstract
We perform single-molecule experiments and simulations to study the swelling of complex knots in linearly extended DNA molecules. We induce self-entanglement of DNA molecules in a microfluidic T-junction using an electrohydrodynamic instability and then stretch the molecules using divergent electric fields. After the chain is fully extended, the knot appears as a region of excess fluorescent brightness, and we shut off the field and observe the...
Paper Details
Title
Dynamics of DNA Knots during Chain Relaxation
Published Date
May 8, 2017
Volume
50
Issue
10
Pages
4074 - 4082
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