Protective Effect of 18β-Glycyrrhetinic Acid against Triptolide-Induced Hepatotoxicity in Rats

Triptolide (TP) is the major active component of Tripterygium wilfordii Hook F (TWHF) and possesses multiple pharmacological effects. However, hepatotoxicity of TP which is one of the toxic properties slows its progression in clinical application. 18 β -Glycyrrhetinic acid (GA) is the main bioactive ingredient of Licorice ( Glycyrrhiza glabra L.), a herbal medicine famous for its detoxification. This study aims to investigate whether GA...