Original paper
FGF23/FGFR4-mediated left ventricular hypertrophy is reversible
Abstract
Fibroblast growth factor (FGF) 23 is a phosphaturic hormone that directly targets cardiac myocytes via FGF receptor (FGFR) 4 thereby inducing hypertrophic myocyte growth and the development of left ventricular hypertrophy (LVH) in rodents. Serum FGF23 levels are highly elevated in patients with chronic kidney disease (CKD), and it is likely that FGF23 directly contributes to the high rates of LVH and cardiac death in CKD. It is currently unknown...
Paper Details
Title
FGF23/FGFR4-mediated left ventricular hypertrophy is reversible
Published Date
May 16, 2017
Journal
Volume
7
Issue
1
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Notes
History