An Improved Approach for N-Linked Glycan Structure Identification from HCD MS/MS Spectra

Glycosylation is a frequently observed post-translational modification on proteins. Currently, tandem mass spectrometry (MS/MS) serves as an efficient analytical technique for characterizing structures of oligosaccharides. However, developing effective computational approaches for identifying glycan structures from mass spectra is still a great challenge in glycoproteomics research. In this study, we proposed an approach for matching the input...