Original paper
Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer
Abstract
Next-generation sequencing of the exome and genome of prostate cancers has identified numerous genetic alternations. SPOP (Speckle-type POZ Protein) was one of the most frequently mutated genes in primary prostate cancer, suggesting SPOP is a potential driver of prostate cancer development and progression. However, how SPOP mutations contribute to prostate cancer pathogenesis remains poorly understood. SPOP acts as an adaptor protein of the...
Paper Details
Title
Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer
Published Date
Apr 27, 2017
Journal
Volume
13
Issue
4
Pages
e1006748 - e1006748
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Notes
History