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Original paper

Effect of Doxycycline on Epithelial-Mesenchymal Transitionviathe p38/Smad Pathway in Respiratory Epithelial Cells

Volume: 31, Issue: 2, Pages: 71 - 77
Published: Mar 1, 2017
Abstract
Purpose Doxycycline has antibacterial and anti-inflammatory effects, and it also suppresses collagen biosynthesis. This study aimed to confirm the effects and mechanism of doxycycline on transforming growth factor (TGF) beta 1 induced epithelial-mesenchymal transition and cell migration in A549 and primary nasal epithelial cells. Methods A 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide assay and phalloidin-fluorescein isothiocyanate...
Paper Details
Title
Effect of Doxycycline on Epithelial-Mesenchymal Transitionviathe p38/Smad Pathway in Respiratory Epithelial Cells
Published Date
Mar 1, 2017
Volume
31
Issue
2
Pages
71 - 77
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