Three-Dimensional Cell Cultures in Drug Discovery and Development
Abstract
The past decades have witnessed significant efforts toward the development of three-dimensional (3D) cell cultures as systems that better mimic in vivo physiology. Today, 3D cell cultures are emerging, not only as a new tool in early drug discovery but also as potential therapeutics to treat disease. In this review, we assess leading 3D cell culture technologies and their impact on drug discovery, including spheroids, organoids, scaffolds,...
Paper Details
Title
Three-Dimensional Cell Cultures in Drug Discovery and Development
Published Date
Jun 1, 2017
Journal
Volume
22
Issue
5
Pages
456 - 472
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