Review paper
The “rectosigmoid brake”: Review of an emerging neuromodulation target for colorectal functional disorders
Volume: 44, Issue: 7, Pages: 719 - 728
Published: Jun 28, 2017
Abstract
The regulation of gastrointestinal motility encompasses several overlapping mechanisms including highly regulated and coordinated neurohormonal circuits. Various feedback mechanisms or "brakes" have been proposed. While duodenal, jejunal, and ileal brakes are well described, a putative distal colonic brake is less well defined. Despite the high prevalence of colonic motility disorders, there is little knowledge of colonic motility owing to...
Paper Details
Title
The “rectosigmoid brake”: Review of an emerging neuromodulation target for colorectal functional disorders
Published Date
Jun 28, 2017
Volume
44
Issue
7
Pages
719 - 728
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