Engineering bacterial thiosulfate and tetrathionate sensors for detecting gut inflammation

Volume: 13, Issue: 4
Published: Apr 1, 2017
Abstract
There is a groundswell of interest in using genetically engineered sensor bacteria to study gut microbiota pathways, and diagnose or treat associated diseases. Here, we computationally identify the first biological thiosulfate sensor and an improved tetrathionate sensor, both two‐component systems from marine Shewanella species, and validate them in laboratory Escherichia coli . Then, we port these sensors into a gut‐adapted probiotic E. coli...
Paper Details
Title
Engineering bacterial thiosulfate and tetrathionate sensors for detecting gut inflammation
Published Date
Apr 1, 2017
Volume
13
Issue
4
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.