Review paper
Synthetic Random Copolymers as a Molecular Platform To Mimic Host-Defense Antimicrobial Peptides
Abstract
Synthetic polymers have been used as a molecular platform to develop host-defense antimicrobial peptide (AMP) mimetics which are effective in killing drug-resistant bacteria. In this topical review, we will discuss the AMP-mimetic design and chemical optimization strategies as well as the biological and biophysical implications of AMP mimicry by synthetic polymers. Traditionally, synthetic polymers have been used as a chemical means to replicate...
Paper Details
Title
Synthetic Random Copolymers as a Molecular Platform To Mimic Host-Defense Antimicrobial Peptides
Published Date
Apr 17, 2017
Journal
Volume
28
Issue
5
Pages
1340 - 1350
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