Optometry

Neuroscience

Biology

Gene

Genetic enhancement

Genetics

Medicine

Ophthalmology

Retinal

Molecular Therapy

Over the past 20 years, there has been tremendous progress in retinal gene therapy. The safety and efficacy results in one early-onset severe blinding disease may lead to the first gene therapy drug approval in the United States. Here, we review how far the field has come over the past two decades and speculate on the directions that the field will take in the future.

Taking Stock of Retinal Gene Therapy: Looking Back and Moving Forward