doi.org/10.12688/f1000research.9692.1
Review paper

Advances in understanding the renin-angiotensin-aldosterone system (RAAS) in blood pressure control and recent pivotal trials of RAAS blockade in heart failure and diabetic nephropathy

Lama Ghazi
10
,
Paul E. Drawz
26
F1000Research
Volume: 6, Pages: 297 - 297
Published: Mar 21, 2017
Abstract
The renin-angiotensin-aldosterone system (RAAS) plays a fundamental role in the physiology of blood pressure control and the pathophysiology of hypertension (HTN) with effects on vascular tone, sodium retention, oxidative stress, fibrosis, sympathetic tone, and inflammation. Fortunately, RAAS blocking agents have been available to treat HTN since the 1970s and newer medications are being developed. In this review, we will (1) examine new...
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Paper Details
Title
Advances in understanding the renin-angiotensin-aldosterone system (RAAS) in blood pressure control and recent pivotal trials of RAAS blockade in heart failure and diabetic nephropathy
DOI
doi.org/10.12688/f1000research.9692.1
Published Date
Mar 21, 2017
Journal
F1000Research
Volume
6
Pages
297 - 297
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