Prevalence of p53 codon 72, p73 G4C14-A4T14 and MDM2 T309G polymorphisms and its association with the risk of oral cancer in South Indians

Genetic susceptibility to cancer through single nucleotide polymorphisms - p53 Pro72Arg, p73 G4C14-A4T14 (two linked polymorphism) and MDM2 T309G has been reported in various ethnic populations. Yet the association is unclear in oral cancer of Indian origin where tobacco chewing is widely practiced. The aim of the study was to evaluate the significance of these polymorphisms for the development of oral cancer. Single Nucleotide Polymorphisms...