Joint system relaxometry (JSR) and Crámer‐Rao lower bound optimization of sequence parameters: A framework for enhanced precision of DESPOT T1 and T2 estimation
Abstract
Purpose This study aims to increase the precision of single‐compartment DESPOT relaxometry by two means: (i) a joint system relaxometry (JSR) approach that estimates parameters in a single step using all available data; and (ii) optimizing acquisition parameters by deploying a robust design tool based on the Crámer‐Rao lower bound (CRLB). Methods Following the development of the analysis and design capabilities, phantom and four in vivo subject...
Paper Details
Title
Joint system relaxometry (JSR) and Crámer‐Rao lower bound optimization of sequence parameters: A framework for enhanced precision of DESPOT T1 and T2 estimation
Published Date
Mar 16, 2017
Volume
79
Issue
1
Pages
234 - 245
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