Lower blood pressure and risk of cisplatin nephrotoxicity: a retrospective cohort study

The pathophysiological mechanisms of cisplatin nephrotoxicity include the reduction of renal blood flow, as well as tubular epithelial cell toxicity. The objective of this study was to investigate the influence of lower blood pressure and decreased food intake on the incidence of cisplatin nephrotoxicity.We conducted a retrospective cohort study at a university hospital between 2011 and 2012. We identified hospitalized adult patients with head...