Preparation and in-vitro/in-vivo characterization of trans-resveratrol nanocrystals for oral administration

Trans null null null null null null null null null null null null null null null null null null null null null null null -resveratrol (t-RES) is a natural polyphenolic compound with extensive therapeutic activities; however, its clinical application is circumscribed due to its poor solubility and low bioavailability. The purpose of this study was to prepare stable t-RES nanocrystals (t-RES-NCs) with different stabilizers to improve its oral...