Original paper
Rational Design of a Polymer with Robust Efficacy for Intracellular Protein and Peptide Delivery
Abstract
The efficient delivery of biopharmaceutical drugs such as proteins and peptides into the cytosol of target cells poses substantial challenges owing to their large size and susceptibility to degradation. Current protein delivery vehicles have limitations such as the need for protein modification, insufficient delivery of large-size proteins or small peptides, and loss of protein function after the delivery. Here, we adopted a rational approach to...
Paper Details
Title
Rational Design of a Polymer with Robust Efficacy for Intracellular Protein and Peptide Delivery
Published Date
Feb 16, 2017
Journal
Volume
17
Issue
3
Pages
1678 - 1684