Identifying cancer patients at high risk for chemotherapy-induced nausea and vomiting (CINV): the development of a prediction tool

Nausea and vomiting (N&V) remain among the most feared side effects of chemotherapy (CT). In addition to type of CT, several patient risk factors for CINV have been consistently reported in the literature. A large dataset was assembled to develop a repeated measures cycle based model that would accurately predict the risk of ≥ grade 2 CINV (≥3 vomiting episodes) over 5 days post CT. CINV outcomes and risk factor data were obtained from 1198...