Protective Effects of Melatonin on the Activity of SOD, CAT, GSH-Px and GSH Content in Organs of Mice after Administration of SNP
Abstract
Sodium nitroprusside (SNP) is an antihypertensive drug with proven dose-dependent toxic effects attributed mainly to the production of cyanide but also excesive nitric oxide (NO) and derived reactive species. The present study evaluated whether melatonin administration would have time-dependent protective effect against SNP−induced toxicity. Male Swiss mice were used in this study. Control mice were treated with 0.9% NaCl; the second group was...
Paper Details
Title
Protective Effects of Melatonin on the Activity of SOD, CAT, GSH-Px and GSH Content in Organs of Mice after Administration of SNP
Published Date
Feb 28, 2017
Volume
60
Issue
1
Pages
1 - 10
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