Abstract 334: Glucose regulates chemoresistance and stemness via Wnt/β-catenin signaling in ovarian cancer cells

Glucose metabolic alteration is one of the hallmarks of ovarian cancer. Here, we first demonstrated the function of glucose as a signature molecule that regulated chemosensitivities in ovarian cancer cells. To verify the role of glucose on the chemoresistance in ovarian cancer cells, we used various concentrations of glucose containing media (0 mM to 20 mM). Glucose reduction inhibited proliferation of various ovarian cancer cell types;...