Lumican -null mice are susceptible to aging and isoproterenol-induced myocardial fibrosis
Volume: 482, Issue: 4, Pages: 1304 - 1311
Published: Jan 1, 2017
Abstract
With aging and stress, the myocardium undergoes structural remodeling, often leading to fibrosis. The purpose of this study is to examine whether lumican, one of the class II small leucine-rich proteoglycans, has a protective role in cardiac remodeling and fibrosis. In attempts to elucidate the hypothesis that lumican may have a protective role in cardiac remodeling and fibrosis, we compared the cardiac phenotypes of young (3-month-old) and...
Paper Details
Title
Lumican -null mice are susceptible to aging and isoproterenol-induced myocardial fibrosis
Published Date
Jan 1, 2017
Volume
482
Issue
4
Pages
1304 - 1311
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