INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES (Int. J. of Pharm. Life Sci.) Isolation and structural characterization of Imipramine hydrochloride degradation impurities and development of stability-indicating UPLC method
Published: Jan 1, 2014
Abstract
A novel, high-throughput, reverse phase-ultra performance liquid chromatographic (RP-UPLC) method has been developed for the quantification of Imipramine and its related impurities in drug substance. The stability-indicating capability of the developed method is demonstrated using forced degradation samples from stress conditions such as hydrolysis, oxidation, thermal and photolytic degradation. During forced degradation it has been observed...
Paper Details
Title
INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES (Int. J. of Pharm. Life Sci.) Isolation and structural characterization of Imipramine hydrochloride degradation impurities and development of stability-indicating UPLC method
Published Date
Jan 1, 2014
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