Periosteum mechanobiology and mechanistic insights for regenerative medicine.

Published on Nov 30, 2016in bonekey Reports
6.87
· DOI :10.1038/bonekey.2016.70
Melissa L. Knothe Tate30
Estimated H-index: 30
(UNSW: UNSW Sydney),
Nicole Y C Yu14
Estimated H-index: 14
(UNSW: UNSW Sydney)
+ 2 AuthorsUlf Knothe18
Estimated H-index: 18
(TissuTex Pty. Ltd. , Wentworth Falls)
Source
Abstract
Periosteum is a smart mechanobiological material that serves as a habitat and delivery vehicle for stem cells as well as biological factors that modulate tissue genesis and healing. Periosteum's remarkable regenerative capacity has been harnessed clinically for over two hundred years. Scientific studies over the past decade have begun to decipher the mechanobiology of periosteum, which has a significant role in its regenerative capacity. This integrative review outlines recent mechanobiological insights that are key to modulating and translating periosteum and its resident stem cells in a regenerative medicine context.
References54
Cited By11
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