The Aryl Hydrocarbon Receptor and Its Ligands Inhibit Myofibroblast Formation and Activation
Volume: 186, Issue: 12, Pages: 3189 - 3202
Published: Dec 1, 2016
Abstract
Thyroid eye disease (TED) is a degenerative disease that manifests with detrimental tissue remodeling, myofibroblast accumulation, and scarring in the orbit of affected individuals. Currently, there are no effective therapies for TED that target or prevent the excessive tissue remodeling caused by myofibroblast formation and activation. The canonical cytokine that induces myofibroblast formation is transforming growth factor (TGF)-β. The TGF-β...
Paper Details
Title
The Aryl Hydrocarbon Receptor and Its Ligands Inhibit Myofibroblast Formation and Activation
Published Date
Dec 1, 2016
Volume
186
Issue
12
Pages
3189 - 3202
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