Cardiac Remodeling in Patients With Primary and Secondary Aldosteronism

Background— Primary aldosteronism (PA) causes excess left ventricular (LV) hypertrophy and diastolic dysfunction; whether this occurs also in secondary aldosteronism (SA) without hypertension is unknown. We investigated the cardiac modifications in patients with preserved LV ejection fraction who had PA or SA. Methods and Results— We measured several Doppler echocardiography–derived variables, including tissue Doppler imaging (TDI) parameters...