Review paper

Pentraxins in the activation and regulation of innate immunity

Volume: 274, Issue: 1, Pages: 202 - 217
Published: Oct 26, 2016
Abstract
Humoral fluid phase pattern recognition molecules (PRMs) are a key component of the activation and regulation of innate immunity. Humoral PRMs are diverse. We focused on the long pentraxin PTX3 as a paradigmatic example of fluid phase PRMs. PTX3 acts as a functional ancestor of antibodies and plays a non-redundant role in resistance against selected microbes in mouse and man and in the regulation of inflammation. This molecule interacts with...
Paper Details
Title
Pentraxins in the activation and regulation of innate immunity
Published Date
Oct 26, 2016
Volume
274
Issue
1
Pages
202 - 217
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