Familial Icterus Gravis of the New-Born and its Treatment.

Published on Oct 1, 1925in Canadian Medical Association Journal8.262
Hart Ap1
Estimated H-index: 1
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1 Author (L. K. Diamond)
Cited By31
#1Thor Willy Ruud Hansen (University of Oslo)H-Index: 30
#2M. Jeffrey Maisels (Oakland University)H-Index: 36
Last. Vinod K. Bhutani (Stanford University)H-Index: 61
view all 7 authors...
A breakthrough discovery 60 years ago by Cremer et al. has since changed the way we treat infants with hyperbilirubinemia and saved the lives of millions from death and disabilities. “Photobiology” has evolved by inquiry of diverse light sources: fluorescent tubes (wavelength range of 400–520 nm; halogen spotlights that emit circular footprints of light; fiberoptic pads/blankets (mostly, 400–550 nm range) that can be placed in direct contact with skin; and the current narrow-band blue light-emit...
#1Orna Rosen (Montefiore Medical Center)H-Index: 1
#2Robert Angert (NYU: New York University)H-Index: 1
This technical report describes the creation of two exchange transfusion models in the newborn. These are low cost, easy to assemble, authentic, and realistic task trainers that provide the opportunity for neonatal providers to practice this rare, life-saving procedure. A critical action checklist is included to guide the simulated procedure. Also included is a suggested clinical scenario with optional complications and variations.
Aims: The present study was done to assess the usefulness of the cord blood bilirubin estimation as a predictor of subsequent neonatal hyperbilirubinemia in a healthy term infants who require phototherapy. Setting and Design: A prospective cohort study was conducted at tertiary care centre. 100 term newborn delivered by LSCS was included in this study. Methods and Materials: 5ml of blood was collected from umbilical cord during delivery. It was used for estimation for conjugated, unconjugated, t...
#1Horacio S. Falciglia (Cincinnati Children's Hospital Medical Center)H-Index: 2
Once commonly performed in the NICU, double volume exchange transfusion has become a rare procedure due to the prevention of hemolytic disease of the newborn and changes in detection and management of hyperbilirubinemia. Despite these advances, the procedure remains an important tool in the neonatologist’s armamentarium to reduce bilirubin levels. In this article, the indications, practical considerations, and the technique of exchange transfusion are reviewed to ensure that this skill is not a ...
Ancient concepts of the blood were described by Hippocrates and Galen 2000 years ago in their doctrine of “humors.” It was believed that the body was made up of four humors – blood, phlegm, black bile, and yellow bile – and that these four components had the qualities of heat (Hot-blooded!), cold, moist, and dry. The Galenic concept of the blood prevailed through the Middle Ages. Health or disease were a result of an imbalance, between these humors. This was the basis of the practice of thera pe...
Treatment of sick neonates originated in maternity and foundling hospitals in the 19th century. Nosocomial infections and difficult logistics of wet-nursing prevented admission of neonates in most chi
Objectives: To review the range of thresholds used for treatment of neonatal jaundice at different gestational ages across neonatal units in Great Britain. To investigate the time at which the threshold values plateau, in terms of hours after birth, for various gestational ages. Methods: We contacted 72 neonatal units in Great Britain and enquired about the unit guidelines for management of neonatal jaundice. We requested a copy of the guidelines and jaundice action charts used. Levels for treat...
Abstract. Jaundice is the most common reason for doing blood tests and starting therapy in newborn infants. In some neonates serum bilirubin levels may become excessively high, and in rare instances this may lead to brain damage ( kernicterus ). In such cases it is important to start treatment quickly. Herein we will discuss various approaches through which serum bilirubin levels may be reduced, thus potentially preventing brain damage. This paper is based on relevant publications found through ...
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